Older people with CVD usually have multiple chronic conditions which are often addressed by guidelines that focus on a single disease, an approach that can increase the risk of inappropriate polypharmacy. Its prevalence increases with older age, reaching 80% in people above the age of 75. Hypertension is a major risk factor for cardiovascular disease (CVD). Future studies will be needed to determine the effect of UV light in different samples of the population and especially in a population with hypertension. UV light had only a short-term effect but not a long-term effect on blood pressure reduction compared to VD use in this sample of normotensive to mild hypertensive nursing home residents with dementia. With the VD group as a reference, the estimated difference in mean change of systolic blood pressure was − 26.0 mmHg at 1 month, 4.5 mmHg (95% CI -6.8, 15.9, p = 0.432) at 3 months, and 0.1 (95% CI -14.1, 14.3, p = 0.83) at 6 months. Differences in blood pressure changes were assessed using linear mixed models. Short-term effects were evaluated after 1 month and long-term effects after 3 and 6 months. The participants received half-body UV irradiation, twice weekly over 6 months, at one standard erythema dose (UV group, n = 22) or 5600 international units of cholecalciferol once a week (VD group, n = 39). Post-hoc analysis of randomized controlled trial data concerning nursing home residents with dementia ( N = 61 41 women, mean age 84.8 years). The aim of this study was to assess differences in blood pressure changes between persons with dementia receiving UV light versus vitamin D (VD) supplementation. Observational studies have reported an inverse association between ultraviolet (UV) radiation and hypertension.
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